Effects that can be expected with oral intake
Effects that can be expected with parenteral administration
Liposomes are spherical vesicles consisting of one or more phospholipid bilayers surrounding an aqueous cavity and they are highly reminiscent of natural cells. Hydrophobic drugs/natural compounds can be encapsulated within the lipid bilayer of the liposomes, whereas water-soluble compounds can be loaded into the aqueous interior cavity.
Liposomes are the most intensely investigated nanocarriers in the field of targeted drug delivery. Several liposome-based drugs have been clinically approved to treat diseases ranging from cancers to infections, demonstrating their versatility and applicability in drug delivery. Liposomes can significantly change pharmacokinetics and lower toxicity of drug products. Moreover, liposomes are highly biocompatible and biodegradable, show low immunogenicity, and they can be easily surface functionalized for targeted, sustained and prolonged release.
Next to pharmaceutical applications liposomes are widely applied in functional food products. They help disperse poorly soluble (lipophilic) supplement ingredients.
Furthermore, liposomes help to protect active ingredients from the harsh environment of the gastrointestinal tract. Once arrived at the intestine the liposomes help the uptake of the active ingredients in the body. Together these actions contribute to an increased uptake and bioavailability of nutritional supplements.
LIPOSOMA has decades of expertise in liposomal product formulations in various fields, like pharma, food, cosmetics and medical devices. For more information about liposome custom manufacturing of food, pharma and other applications, branded and white label products, contact our sales and/or business development department.